Aβ1–42 aggregation inhibitor 1

CAT:

804-HY-150003-02

Size:

10 mM / 1 mL

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CAS Number: 2439107-75-0
UNSPSC Description: Aβ1-42 aggregation inhibitor 1 inhibits AChE (acetylcholinesterase) and BuChE (butyrylcholinesterase) with the IC50 value of 2.64 μM and 1.29 μM, respectively. Aβ1-42 aggregation inhibitor 1 inhibits self-mediated Aβ1-42 aggregation by 51.29% at a concentration of 25 μM. Aβ1-42 aggregation inhibitor 1 has the potential for the research of anti-Alzheimer's disease[1].
Target Antigen: Amyloid-β; Cholinesterase (ChE)
Type: Reference compound
Related Pathways: Neuronal Signaling
Applications: Neuroscience-Neurodegeneration
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/aβ1-42-aggregation-inhibitor-1.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: CCN1C2=CC=C(/C=C/C3=CC=C(C=C3)NC(NCCN4CCCC4)=S)C=C2C5=CC=CC=C51
Molecular Weight: 468.66
References & Citations: [1]Dushyant V Patel, et al. Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents. Bioorg Chem. 2020 Aug;101:103977.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-150003-01	Aβ1–42 aggregation inhibitor 1
HY-150003-04	Aβ1–42 aggregation inhibitor 1
HY-150003-02	Aβ1–42 aggregation inhibitor 1
HY-162093	Aβ1–42 aggregation inhibitor 2
HY-150003-03	Aβ1–42 aggregation inhibitor 1
HY-150003-05	Aβ1–42 aggregation inhibitor 1
HY-144389	hAChE/Aβ1-42-IN-1
HY-144388	ChE/Aβ1-42-IN-1
HY-125172	PolyQ aggregation inhibitor C2-8
HY-160853	Tubulin inhibitor 42

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