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RS-51324

CAT: 0804-HY-123398Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123398Size:1 Each
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Description
RS-51324 is an orally active antidepressant and a potent membrane pump inhibitor. RS-51324 inhibits norepinephrine uptake and reverses reserpine -induced hypothermia. Although lacking MAO inhibition and anticholinergic activity, RS-51324 enhances the effects of L-DOPA (a metabolic precursor of dopamine), potentiates tyramine-induced pressor responses, and has mild antihistamine activity. The LD50 of RS-51324 is >2 g/kg[1][2].
CAS Number
69811-30-9
UNSPSC
12352005
Target
Adrenergic Receptor; Dopamine Receptor; Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rs-51324.html
Smiles
O=C(NC1=NCC(C2=C(C=CC=C2Cl)Cl)N1)OC
Molecular Formula
C11H11Cl2N3O2
Molecular Weight
288.13
References & Citations
[1]Wallach MB, et al. The neuro- and cardiovascular pharmacology of RS-51324, a potential antidepressant. Prog Neuropsychopharmacol. 1980;4 (6) :569-84. |[2]Wallach M B, et al. The neuro-and cardiovascular pharmacology of RS-51324, a potential antidepressant[J]. Progress in Neuro-Psychopharmacology, 1981, 4 (6) : 569-584.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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