Anticancer agent 245

• Description:

  Anticancer agent 245 (Compound 115) inhibits proliferation of cancer cell SKOV3, MDA-MB-231 and HCT-116 with IC50 of 0.021, 0.056 and 0.11 μM, respectively. Anticancer agent 245 exhibits antitumor efficacy in mice and good pharmacokinetic characteristics in rat models[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-245.html

• Smiles:

  O=C(CCC1=C(B(OC2)O)C2=CC=C1)NC3=CC(C4=CC=C(C(C)=O)C=C4)=CC=C3

• Molecular Formula:

  C24H22BNO4

• Molecular Weight:

  399.25

• References & Citations:

  [1]Zhang J, et al., Design, Synthesis, and Structure-Activity Relationship of 7-Propanamide Benzoxaboroles as Potent Anticancer Agents. J Med Chem. 2019 Jul 25;62 (14) :6765-6784.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2130040-60-5]