Anticancer agent 245

CAT: 0804-HY-164320Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-164320Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anticancer agent 245 (Compound 115) inhibits proliferation of cancer cell SKOV3, MDA-MB-231 and HCT-116 with IC50 of 0.021, 0.056 and 0.11 μM, respectively. Anticancer agent 245 exhibits antitumor efficacy in mice and good pharmacokinetic characteristics in rat models[1].
CAS Number
[2130040-60-5]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-245.html
Smiles
O=C(CCC1=C(B(OC2)O)C2=CC=C1)NC3=CC(C4=CC=C(C(C)=O)C=C4)=CC=C3
Molecular Formula
C24H22BNO4
Molecular Weight
399.25
References & Citations
[1]Zhang J, et al., Design, Synthesis, and Structure-Activity Relationship of 7-Propanamide Benzoxaboroles as Potent Anticancer Agents. J Med Chem. 2019 Jul 25;62 (14) :6765-6784.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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