sEH/HDAC6-IN-2

• UNSPSC Description:

  sEH/HDAC6-IN-2 is a potent dual soluble epoxide hydrolase (sEH) and HDAC6 inhibitor with IC50s of 0.9 nM, 46.8 nM, and 8 nM for human sEH, mouse sEH, and HDAC6, respectively. sEH/HDAC6-IN-2 can be used for the study of inflammatory pain[1].

• Target Antigen:

  Epoxide Hydrolase; HDAC

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/seh-hdac6-in-2.html

• Smiles:

  O=C([C@@H]1CN(C(C2=CC=C(NC(NC3=CC=C(Cl)C(F)=C3)=O)C(F)=C2)=O)CCC1)NCCCCCCC(NO)=O

• Molecular Weight:

  580.02

• References & Citations:

  [1]Huashen Xu , et al. Design and Synthesis of sEH/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain. J Med Chem. 2024 Jul 21.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3009011-58-6