Fl-DIBO

CAT: 0804-HY-D1506-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-D1506-01Size:5 mg
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Description
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference[1][2]. Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[1407523-31-2]
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fl-dibo.html
Purity
99.28
Solubility
10 mM in DMSO
Smiles
O=C1C2=C1C3=CC=C(OC)C=C3C#CC4=C2C=CC(OC)=C4
Molecular Formula
C19H12O3
Molecular Weight
288.30
References & Citations
[1]Ke Wang, et al. A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides. Bioorg Med Chem Lett. 2016 Apr 1;26 (7) :1651-4.|[2] Frédéric Friscourt, et al. Fluorogenic Strain-Promoted Alkyne-Diazo Cycloadditions. Chemistry. 2015 Sep 28;21 (40) :13996-4001. doi: 10.1002/chem.201502242. Epub 2015 Aug 18.|[3]Camille Favre, et al. Sydnone Reporters for Highly Fluorogenic Copper-Free Click Ligations. J Org Chem. 2018 Feb 16;83 (4) :2058-2066.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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