BODIPY-FL

• Description:

  BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. BODIPY-FL-labeled sphingolipid analogs can be used to investigate sphingolipid internalization, transport, and endocytosis in mouse embryonic stem cells. BODIPY-FL-labeled monoterpenes can quickly penetrate bacteria, mammalian, and fungal cells, allowing for the detection of characteristics of a broad spectrum of Gram-positive and Gram-negative bacteria, as well as pathogenic fungi. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm[1][2][3][4].

• UNSPSC:

  12171500

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bodipy-fl.html

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(CCC1=CC=C2C=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]21)[F-])O

• Molecular Formula:

  C14H15BF2N2O2

• Molecular Weight:

  292.09

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Leung K. BODIPY-FL-neutravidin-biotin-Cetuximab. 2008 Jan 15 [updated 2008 Feb 25]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD) : National Center for Biotechnology Information (US) ; 2004–2013. PMID: 20641313.|[2]Kurata S, et al. Fluorescent quenching-based quantitative detection of specific DNA/RNA using a BODIPY ((R) ) FL-labeled probe or primer. Nucleic Acids Res. 2001 Mar 15;29 (6) :E34. |[3]Fan W, et al. Using BODIPY FL-Sphingolipid Analogs to Study Sphingolipid Metabolism in Mouse Embryonic Stem Cells. Bio Protoc. 2022 Nov 20;12 (22) :e4555.|[4]Guseva GB, et al. Design, Spectral Characteristics, and Possibilities for Practical Application of BODIPY FL-Labeled Monoterpenoid. ACS Appl Bio Mater. 2021 Aug 16;4 (8) :6227-6235.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [165599-63-3]