FL-411

CAT: 0804-HY-111102-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-111102-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FL-411 is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4 (1) .
CAS Number
[2118944-88-8]
Product Name Alternative
BRD4-IN-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/FL-411.html
Purity
99.05
Solubility
DMSO : 5.4 mg/mL (ultrasonic)
Smiles
CN1CCC2=C(SC(N=C(C3=CC(C)=C(O)C(C)=C3)N4)=C2C4=O)C1
Molecular Formula
C18H19N3O2S
Molecular Weight
341.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Ouyang L, et al. Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That InducesAMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer. J Med Chem. 2017 Dec 28;60 (24) :9990-10012.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4

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C07448FL-411
A19506-2FL-411 2mg
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A19506-50FL-411 50mg
A19506-10FL-411 10mg
A19506-100FL-411 100mg
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