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TNIK-IN-8

CAT: 0804-HY-162314-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162314-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TNIK-IN-8 (Compound 35b) is a potent, orally active TNKI inhibitor with a IC50 value of 6 nM. TNIK-IN-8 has antitumor activity[1].
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tnik-in-8.html
Purity
99.58
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(O)(C)C#CC1=CC(C=C(C2=C(C3=CC=C(F)C=C3)N=CN2C)C=C4)=C4N=C1
Molecular Formula
C24H20FN3O
Molecular Weight
385.43
References & Citations
[1]Teng Y, et al. Fragment growth-based discovery of novel TNIK inhibitors for the treatment of colorectal cancer. Eur J Med Chem. 2024 Feb 24;268:116240.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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