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TNIK-IN-1

CAT: 0804-HY-124762-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-124762-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TNIK-IN-1 (Compound 1) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 65 nM, that has antitumor activity[1].
CAS Number
933886-36-3
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tnik-in-1.html
Purity
98.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(NC(C2=CC=C(NC(C)=O)C=C2)=O)SC(NC3=CC=CC=C3)=N1)N
Molecular Formula
C19H17N5O3S
Molecular Weight
395.43
References & Citations
[1]Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23 (2) :569-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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