TNIK-IN-1

TNIK-IN-1

• CAS Number: 933886-36-3
• UNSPSC Description: TNIK-IN-1 (Compound 1) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 65 nM, that has antitumor activity[1].
• Target Antigen: Ser/Thr Protease
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/tnik-in-1.html
• Purity: 98.86
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=C(NC(C2=CC=C(NC(C)=O)C=C2)=O)SC(NC3=CC=CC=C3)=N1)N
• Molecular Weight: 395.43
• References & Citations: [1]Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported