Products for Research Use Only
RegisterLogin

CXCR7 Rabbit Polyclonal Antibody

CAT: 0992-R1512-3Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-R1512-3Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
CAS Number
9007-83-4
Product Name Alternative
ACKR3 antibody atypical chemokine receptor 3 antibody C X C chemokine receptor type 7 antibody C-X-C chemokine receptor type 7 antibody Chemokine (C-X-C motif) receptor 7 antibody Chemokine C X C motif receptor 7 antibody Chemokine orphan receptor 1 antibody CMKOR1 antibody CXC R7 antibody CXC-R7 antibody CXCR 7 antibody CXCR-7 antibody CXCR7 antibody CXCR7_HUMAN antibody G protein coupled receptor 159 antibody G protein coupled receptor antibody G protein coupled receptor RDC1 homolog antibody G-protein coupled receptor 159 antibody G-protein coupled receptor RDC1 homolog antibody GPCR RDC1 antibody GPR159 antibody GPRN1 antibody RDC 1 antibody RDC-1 antibody RDC1 antibody
Abbreviation
Atypical chemokine receptor 3 C-X-C chemokine receptor type 7 CXC-R7 CXCR-7 Chemokine orphan receptor 1 G-protein coupled receptor 159 G-protein coupled receptor RDC1 homolog RDC-1
Swiss Prot
P25106 Human
Cellular Locus
Cell membrane, Cytoplasm, Endosome, Membrane
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within C terminal human CXCR7.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
Hela cell lysate, MCF-7 cell lysate, Jurkat cell lysate, Hela, HUVEC, MCF-7.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
ET1611-3CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09]
HA500526CXCR1 Rabbit Polyclonal Antibody
ER1802-28CXCR4 Rabbit Polyclonal Antibody
ER1906-87CXCR2 Rabbit polyclonal Antibody
HA750422CXCR3 Recombinant Rabbit monoclonal Antibody
HA750463CXCR5 Recombinant Rabbit monoclonal Antibody
ER1901-73GABARAPL2 Rabbit Polyclonal Antibody
ER2001-53Transferrin Rabbit Polyclonal Antibody
ER1802-12LSD1 Rabbit Polyclonal Antibody
HA500270AIM2 Rabbit Polyclonal Antibody

Alternative Products

CatalogName
GTR18307886CXCR7 Rabbit Polyclonal Antibody
MBS2554685-01CXCR7 Polyclonal Antibody
NBP2-24779SSRabbit Polyclonal CXCR7/RDC-1 Antibody
A03069-50CXCR7 Antibody, mAb, Rabbit
E49Y5686CXCR7 Rabbit Monoclonal Antibody
GTR18042062-01CXCR7 (A356) polyclonal antibody
GTR18335470-01CXCR7 Rabbit mAb Antibody
MBS244797-01Rabbit Polyclonal to Human ACKR3 / CXCR7
NBP2-24779FRabbit Polyclonal CXCR7/RDC-1 Antibody [FITC]
NBP2-24779BRabbit Polyclonal CXCR7/RDC-1 Antibody [Biotin]

Popular Products