CXCR1 Rabbit Polyclonal Antibody

CXCR1 Rabbit Polyclonal Antibody

• Description: Interleukin 8 receptor, alpha is a chemokine receptor. This name and the corresponding gene symbol IL8RA have been replaced by the HGNC approved name C-X-C motif chemokine receptor 1 and the approved symbol CXCR1. It has also been designated as CD181 (cluster of differentiation 181). The IUPHAR Committee on Receptor Nomenclature and Drug Classification use the HGNC recommended name, CXCR1. The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. IL8RA, IL8RB, which encodes another high affinity IL8 receptor, and IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Stimulation of CXCR1 in neutrophils by its primary ligand, Interleukin 8, leads to neutrophil chemotaxis and activation.
• Product Name Alternative: C C antibody C C CKR 1 antibody C-X-C chemokine receptor type 1 antibody CCCKR1 antibody CD 181 antibody CD128 antibody CD181 antibody CD181 antigen antibody CDw128a antibody Chemokine (C X C motif) receptor 1 antibody Chemokine (C X C) receptor 1 antibody Chemokine receptor 1 antibody CKR 1 antibody CMKAR1 antibody CXC-R1 antibody CXCR 1 antibody CXCR-1 antibody CXCR1 antibody CXCR1_HUMAN antibody High affinity interleukin 8 receptor A antibody High affinity interleukin-8 receptor A antibody IL 8 receptor type 1 antibody IL 8R A antibody IL-8 receptor type 1 antibody IL-8R A antibody IL8 receptor antibody IL8 receptor type 1 antibody IL8R1 antibody IL8RA antibody IL8RBA antibody Interleukin 8 receptor alpha antibody Interleukin 8 receptor type 1 antibody Interleukin 8 receptor type A antibody
• Abbreviation: CXCR1, CMKAR1, IL8RA
• CAS Number: 9007-83-4
• Swiss Prot: P25024 Human
• Cellular Locus: Cell membrane.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within full length human CXCR1 protein.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell
• Positive Control: U87-MG cell lysate, Hela cell lysate, Jurkat cell lysate, HepG2 cell lysate, Hela.
• Concentration: 2 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size:
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No