Ku70 Rabbit Polyclonal Antibody

CAT: 0992-R1401-5Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-R1401-5Size:100 µL
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Description
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V (D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system.In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein.
CAS Number
9007-83-4
Product Name Alternative
5'-deoxyribose-5-phosphate lyase Ku70 antibody 5'-dRP lyase Ku70 antibody 70 kDa subunit of Ku antigen antibody ATP dependent DNA helicase 2 subunit 1 antibody ATP dependent DNA helicase II 70 kDa subunit antibody ATP-dependent DNA helicase 2 subunit 1 antibody ATP-dependent DNA helicase II 70 kDa subunit antibody CTC box binding factor 75 kDa subunit antibody CTC box-binding factor 75 kDa subunit antibody CTC75 antibody CTCBF antibody DNA repair protein XRCC6 antibody G22P1 antibody Ku 70 antibody Ku autoantigen p70 subunit antibody Ku autoantigen, 70kDa antibody Ku p70 antibody Ku70 antibody Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa antibody Kup70 antibody Lupus Ku autoantigen protein p70 antibody ML8 antibody Thyroid autoantigen 70kD (Ku antigen) antibody Thyroid autoantigen antibody Thyroid lupus autoantigen antibody Thyroid lupus autoantigen p70 antibody Thyroid-lupus autoantigen antibody TLAA antibody X ray repair complementing defective repair in Chinese hamster cells 6 antibody X-ray repair complementing defective repair in Chinese hamster cells 6 antibody X-ray repair cross-complementing protein 6 antibody XRCC 6 antibody Xrcc6 antibody XRCC6_HUMAN antibody
Abbreviation
5'-dRP lyase Ku70,CTC75,CTCBF,Ku70,TLAA
Swiss Prot
P12956 Human
Cellular Locus
Nucleus
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within N-terminal human Ku70.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
293T, Hela, A431, A549
Concentration
1 mg/mL
Dilution
WB: 1:2000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
70 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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