CD99 Recombinant Rabbit Monoclonal Antibody [PD00-13]

CD99 Recombinant Rabbit Monoclonal Antibody [PD00-13]

• Description: CD99 is a transmembrane glycoprotein, also known as MIC2, involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. It is involved in T-cell adhesion, leukocyte migration and differentiation of primitive neuroectodermal cell. CD99 labels lymphocyte, ovarian granulosa cells, pancreatic islet cells, Sertoli cells, CNS ependymal cells and endothelial cells. CD99 has been useful in diagnosis of Ewing's sarcoma, sex cord-stromal tumor, endocrine tumor of pancreas. Additionally, it is found in a subset of other tumors including lymphoblastic lymphoma, breast carcinoma and other malignancies.
• Product Name Alternative: 12E7 antibody Antigen identified by monoclonal 12E7, Y homolog antibody Antigen identified by monoclonal antibodies 12E7, F21 and O13 antibody CD99 antibody CD99 antigen antibody CD99 molecule antibody CD99_HUMAN antibody Cell surface antigen 12E7 antibody Cell surface antigen HBA 71 antibody Cell surface antigen O13 antibody E2 antigen antibody HBA71 antibody MIC 2X antibody MIC 2Y antibody MIC2 (monoclonal antibody 12E7) antibody MIC2 antibody MIC2X antibody MIC2Y antibody MSK5X antibody Protein MIC2 antibody Surface antigen MIC2 antibody T cell surface glycoprotein E2 antibody T-cell surface glycoprotein E2 antibody
• Abbreviation: CD99
• CAS Number: 9000-83-3
• Swiss Prot: P14209 Human
• Cellular Locus: Membrane.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human CD99 aa 148-185 (Cytoplasmic).
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IHC-P
• Positive Control: Human esophagus tissue, human stomach carcinoma tissue, human ovary granulosa tumor tissue.
• Concentration: 1 mg/mL
• Dilution: IHC-P: 1:1,000-1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 19 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes