KIF5B Recombinant Rabbit Monoclonal Antibody [JE64-16]

KIF5B Recombinant Rabbit Monoclonal Antibody [JE64-16]

• Description: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends. Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells
• Product Name Alternative: Conventional kinesin heavy chain antibody KIF 5B antibody KIF5B antibody Kinesin 1 antibody kinesin 1 (110-120kD) antibody Kinesin 1 heavy chain antibody Kinesin family member 5B antibody Kinesin heavy chain antibody kinesin, heavy chain, ubiquitous antibody Kinesin-1 heavy chain antibody Kinesin1 antibody KINH antibody KINH_HUMAN antibody KNS 1 antibody KNS antibody KNS1 antibody Ubiquitous kinesin heavy chain antibody UKHC antibody
• Abbreviation: KIF5B
• CAS Number: 9000-83-3
• Swiss Prot: P33176 Human, Q61768 Mouse, Q2PQA9 Rat
• Cellular Locus: Cytolytic granule membrane, Lysosome membrane, cytoskeleton.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human KIF5B aa 1-50.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: HeLa cell lysate, A549 cell lysate, mouse kidney tissue lysate, HCT116 cell lysate, C2C12 cell lysate, MCF-7 cell lysate, Hela cell lysate, HepG2 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, human gallbladder tissue, human testis tissue, rat uterus tissue, rat cerebellum tissue lysate, rat bladder tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500 ;IHC-P: 1:100-1:400
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 110 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes