TAB3 Rabbit Polyclonal Antibody

TAB3 Rabbit Polyclonal Antibody

• Description: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
• Product Name Alternative: MAP3K7IP 3 antibody Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 antibody NAP1 antibody NF-kappa-B-activating protein 1 antibody NFkB activating protein 1 antibody TAB-3 antibody Tab3 antibody TAB3_HUMAN antibody TAK1 binding protein 3 antibody TAK1-binding protein 3 antibody TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 antibody TGF-beta-activated kinase 1-binding protein 3 antibody
• Abbreviation: TAB3, MAP3K7IP3
• CAS Number: 9007-83-4
• Swiss Prot: Q8N5C8 Human, Q571K4 Mouse
• Cellular Locus: Cytosol, extracellular exosome, plasma membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Recombinant protein within Human TAB3 aa 513-712 / 712.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: NIH/3T3 cell lysates, human striated muscle tissue.
• Concentration: 1.854 mg/mL
• Dilution: WB: 1:500 ;IHC-P: 1:600
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 79 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No