alpha 1 Spectrin Rabbit Polyclonal Antibody
CAT:
992-HA500357
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
alpha 1 Spectrin Rabbit Polyclonal Antibody
- Description: Spectrin alpha chain, erythrocyte is a protein that in humans is encoded by the SPTA1 gene. Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
- Product Name Alternative: Alpha I spectrin antibody EL 2 antibody EL2 antibody Elliptocytosis 2 antibody Elliptocytosis2 antibody Erythrocyte alpha spectrin antibody erythrocyte antibody Erythroid alpha spectrin antibody Erythroid alpha-spectrin antibody Erythroid spectrin alpha antibody HPP antibody HS3 antibody Spectrin alpha chain antibody Spectrin alpha chain erythrocyte antibody Spectrin alpha erythrocytic 1 antibody SPH3 antibody SPTA 1 antibody SPTA antibody SPTA1 antibody SPTA1_HUMAN antibody
- Abbreviation: SPTA1
- CAS Number: 9007-83-4
- Swiss Prot: P02549 Human, P08032 Mouse
- Cellular Locus: Cytoplasm, Cytoskeleton.
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Recombinant protein within Human alpha 1 Spectrin aa 1-200 / 2,419.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB
- Positive Control: K562 cell lysate, NIH/3T3 cell lysate, A549 cell lysate.
- Concentration: 1 mg/mL
- Dilution: WB: 1:1,000
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 280 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No