Syntrophin alpha 1 Rabbit Polyclonal Antibody
CAT:
992-ER1901-40
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Syntrophin alpha 1 Rabbit Polyclonal Antibody
- Description: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue.
- Product Name Alternative: 59 kDa dystrophin-associated protein A1 acidic component 1 antibody Alpha-1-syntrophin antibody Pro-TGF-alpha cytoplasmic domain-interacting protein 1 antibody SNT1 antibody SNT2 antibody SNT3 antibody Snta1 antibody SNTA1_HUMAN antibody SNTB1 antibody SNTB2 antibody Syntrophin alpha 1 antibody Syntrophin beta 1 antibody Syntrophin beta 2 antibody Syntrophin-1 antibody TACIP1 antibody
- Abbreviation: SNTA1
- CAS Number: 9007-83-4
- Swiss Prot: Q13424 Human, Q61234 Mouse,
- Cellular Locus: Cell junction, Cell membrane, Cytoplasm, Cytoskeleton, Membrane.
- Host: Rabbit
- Species Reactivity: Mouse, Rat, Human
- Immunogen: Synthetic peptide within mouse Syntrophin alpha 1 aa 174-223 / 503.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB
- Positive Control: Mouse skeletal muscle tissue lysate, mouse heart tissue lysate, rat skeletal muscle tissue lysate, rat heart tissue lysate, rat eyeball tissue lysate.
- Concentration: 1 mg/mL
- Dilution: WB: 1:500-1:2,000
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 54 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No