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CCNT1 Rabbit Polyclonal Antibody

CAT: 0992-HA500313Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500313Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). (Microbial infection) In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.
CAS Number
9007-83-4
Product Name Alternative
CCN T1 antibody CCNT antibody CCNT 1 antibody Ccnt1 antibody CCNT1_HUMAN antibody CDK9 associated C type protein antibody Cyc T1 antibody Cyclin C related protein antibody Cyclin T antibody cyclin T1 antibody Cyclin T1b antibody Cyclin-T antibody Cyclin-T1 antibody CYCT 1 antibody CycT1 antibody HIVE1 antibody Human immunodeficiency virus 1 expression antibody Human immunodeficiency virus type 1 (HIV 1) expression (elevated) 1 antibody pTEFb subunit antibody Subunit of positive elongation transcription factor b antibody
Abbreviation
Cyclin-T1 CycT1 Cyclin-T CCNT1
Swiss Prot
O60563 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human CCNT1 aa 275-535 / 726.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
K562 cell lysate, Hela cell lysate, HL-60 cell lysates.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
81 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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