SLC22A2 Rabbit Polyclonal Antibody

• Description:

  Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4- (dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.

• Product Name Alternative:

  MGC32628 antibody OCT 2 antibody OCT2 antibody Organic cation transporter 2 antibody Organic cation transporter antibody RP11-317M22.2 antibody Solute carrier family 22 (organic cation transporter) member 2 antibody Solute carrier family 22 member 2 antibody

• Abbreviation:

  Solute carrier family 22 member 2 Organic cation transporter 2 hOCT2 OCT2

• Swiss Prot:

  O15244 Human, O70577 Mouse, Q9R0W2 Rat

• Cellular Locus:

  Membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human SLC22A2 aa 44-150 / 555 (Extracellular).

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB

• Positive Control:

  HepG2 cell lysate, 293T cell lysate, rat brain tissue lysate, mouse kidney tissue lysate, mouse brain tissue lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB:1:500-1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  63/54/27 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4