SLC22A2 Rabbit Polyclonal Antibody

SLC22A2 Rabbit Polyclonal Antibody

• Description: Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4- (dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.
• Product Name Alternative: MGC32628 antibody OCT 2 antibody OCT2 antibody Organic cation transporter 2 antibody Organic cation transporter antibody RP11-317M22.2 antibody Solute carrier family 22 (organic cation transporter) member 2 antibody Solute carrier family 22 member 2 antibody
• Abbreviation: Solute carrier family 22 member 2 Organic cation transporter 2 hOCT2 OCT2
• CAS Number: 9007-83-4
• Swiss Prot: O15244 Human, O70577 Mouse, Q9R0W2 Rat
• Cellular Locus: Membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human SLC22A2 aa 44-150 / 555 (Extracellular).
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB
• Positive Control: HepG2 cell lysate, 293T cell lysate, rat brain tissue lysate, mouse kidney tissue lysate, mouse brain tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB:1:500-1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 63/54/27 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No