Products for Research Use Only
RegisterLogin

TAZ Rabbit Polyclonal Antibody

CAT: 0992-HA500300Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-HA500300Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis . The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ . WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation . In conjunction with YAP1, involved in the regulation of TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation . Plays a key role in coupling SMADs to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
CAS Number
9007-83-4
Product Name Alternative
DKFZP586I1419 antibody FLJ27004 antibody FLJ45718 antibody OTTHUMP00000215994 antibody OTTHUMP00000215995 antibody OTTHUMP00000215996 antibody OTTHUMP00000216001 antibody TAZ antibody Transcriptional co activator with PDZ binding motif antibody Transcriptional coactivator with PDZ binding motif antibody Transcriptional coactivator with PDZ-binding motif antibody WW domain containing transcription regulator 1 antibody WW domain containing transcription regulator protein 1 antibody WW domain-containing transcription regulator protein 1 antibody WWTR 1 antibody WWTR1 antibody WWTR1_HUMAN antibody
Abbreviation
WW domain-containing transcription regulator protein 1 Transcriptional coactivator with PDZ-binding motif
Swiss Prot
Q9GZV5 Human, Q9EPK5 Mouse
Cellular Locus
Cell membrane, Cytoplasm, Membrane, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human TAZ aa 1-200 / 400.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Human placenta tissue lysate, 293T cell lysate, human kidney tissue, mouse brain tissue, A549, HT-29.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:100-1:500;IF-Cell: 1:100-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA751569TAZ / WWTR1 Recombinant Rabbit monoclonal Antibody
HA751568TAZ / WWTR1 Recombinant Rabbit monoclonal Antibody
HA723764TAZ / WWTR1 Recombinant Rabbit monoclonal Antibody
HA723765TAZ / WWTR1 Recombinant Rabbit monoclonal Antibody
ER1901-73GABARAPL2 Rabbit Polyclonal Antibody
ER2001-53Transferrin Rabbit Polyclonal Antibody
ER1802-12LSD1 Rabbit Polyclonal Antibody
HA500270AIM2 Rabbit Polyclonal Antibody
HA500595TMEM184A Rabbit polyclonal Antibody
HA500594HERC6 Rabbit polyclonal Antibody

Alternative Products

CatalogName
MBS9465999-01Rabbit Polyclonal Antibody PC4 Rabbit Polyclonal Antibody
MBS9465163-01Rabbit Polyclonal Antibody PC1 Rabbit Polyclonal Antibody
TA421149Anti- Rabbit Polyclonal Antibody Rabbit Polyclonal Antibody
GTR18232394-01Rabbit Polyclonal AntibodyPC1 Rabbit Polyclonal Antibody
GTR18231735-01Rabbit Polyclonal AntibodyPC4 Rabbit Polyclonal Antibody
TA354882Rabbit Polyclonal Antibody

Popular Products