PDE6 alpha Rabbit Polyclonal Antibody

PDE6 alpha Rabbit Polyclonal Antibody

• Description: This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
• Product Name Alternative: 5''-cyclic phosphodiesterase subunit alpha antibody CGPR A antibody GMP PDE alpha antibody GMP-PDE alpha antibody PDE 6 alpha antibody PDE 6A antibody PDE V B1 antibody PDE V-B1 antibody PDE6A antibody PDE6A_HUMAN antibody PDEA antibody Phosphodiesterase 6 alpha antibody Phosphodiesterase 6A alpha subunit antibody Phosphodiesterase 6A antibody Phosphodiesterase 6A cGMP specific rod alpha antibody Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha antibody Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit antibody Rod cGMP-specific 3'' antibody
• Abbreviation: PDE6A
• CAS Number: 9007-83-4
• Swiss Prot: P16499 Human, P27664 Mouse,
• Cellular Locus: Cell membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human PDE6 alpha aa 201-400.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: Rat eyeballs tissue lysate, K562 cell lysate, 293T cell lysate, rat kidney tissue lysate, Hela, rat eyeball tissue, mouse eyeball tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500;IF-Cell: 1:200;IHC-P: 1:600
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 100 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No