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Alpha-dystroglycan Rabbit Polyclonal Antibody

CAT: 0992-ER1901-72Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-72Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dystroglycan (DG) is a cell surface receptor for several extracellular matrix molecules including laminins, Agrin and Perlecan. Dystroglycan function is required for the formation of basement membranes in early development and the organization of Laminin on the cell surface. α-dystroglycan is a membrane- associated, extracellular glycoprotein that is anchored to the cell-membrane by binding to the transmembrane glycoprotein α-dystroglycan to form an α/β-dystroglycan-complex. Additionally, dystroglycan is part of a multimolecular complex, where it associates with dystrophin, at the sarcolemma, to form the dystrophin-associated protein complex, or with utrophin, at the neuromuscular junction, to form the utrophin-associated protein complex. Dystroglycan is also thought to participate in the clustering of nicotinic acetylcholine receptors at the neuromuscular junction.
CAS Number
9007-83-4
Product Name Alternative
156DAG antibody A3a antibody AGRNR antibody Alpha dystroglycan antibody Alpha-DG antibody Beta-DG antibody Beta-dystroglycan antibody DAG antibody Dag1 antibody DAG1_HUMAN antibody Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody Dystroglycan antibody Dystrophin associated glycoprotein 1 antibody Dystrophin-associated glycoprotein 1 antibody OTTHUMP00000210857 antibody OTTHUMP00000210858 antibody
Abbreviation
Dystroglycan,Dystrophin-associated glycoprotein 1,Alpha-dystroglycan,Alpha-DG,DAG1,Beta-dystroglycan,Beta-DG
Swiss Prot
Q14118 Human, Q62165 Mouse
Cellular Locus
Cell junction. Cytoplasm. Cytoskeleton. Membrane. Secreted. Synapse. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Alpha-dystroglycan aa 15-64 / 895.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
SkBr3 cell lysate, mouse placenta tissue lysate, SkBr3, Rat skeletal muscle tissue, human placenta tissue, Mouse heart tissue, A431.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 97 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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