Alpha-dystroglycan Rabbit Polyclonal Antibody

Alpha-dystroglycan Rabbit Polyclonal Antibody

• Description: Dystroglycan (DG) is a cell surface receptor for several extracellular matrix molecules including laminins, Agrin and Perlecan. Dystroglycan function is required for the formation of basement membranes in early development and the organization of Laminin on the cell surface. α-dystroglycan is a membrane- associated, extracellular glycoprotein that is anchored to the cell-membrane by binding to the transmembrane glycoprotein α-dystroglycan to form an α/β-dystroglycan-complex. Additionally, dystroglycan is part of a multimolecular complex, where it associates with dystrophin, at the sarcolemma, to form the dystrophin-associated protein complex, or with utrophin, at the neuromuscular junction, to form the utrophin-associated protein complex. Dystroglycan is also thought to participate in the clustering of nicotinic acetylcholine receptors at the neuromuscular junction.
• Product Name Alternative: 156DAG antibody A3a antibody AGRNR antibody Alpha dystroglycan antibody Alpha-DG antibody Beta-DG antibody Beta-dystroglycan antibody DAG antibody Dag1 antibody DAG1_HUMAN antibody Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody Dystroglycan antibody Dystrophin associated glycoprotein 1 antibody Dystrophin-associated glycoprotein 1 antibody OTTHUMP00000210857 antibody OTTHUMP00000210858 antibody
• Abbreviation: Dystroglycan,Dystrophin-associated glycoprotein 1,Alpha-dystroglycan,Alpha-DG,DAG1,Beta-dystroglycan,Beta-DG
• CAS Number: 9007-83-4
• Swiss Prot: Q14118 Human, Q62165 Mouse
• Cellular Locus: Cell junction. Cytoplasm. Cytoskeleton. Membrane. Secreted. Synapse. Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Alpha-dystroglycan aa 15-64 / 895.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, IF-Cell, FC
• Positive Control: SkBr3 cell lysate, mouse placenta tissue lysate, SkBr3, Rat skeletal muscle tissue, human placenta tissue, Mouse heart tissue, A431.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 97 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No