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TTK Rabbit Polyclonal Antibody

CAT: 0992-HA500249Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500249Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Product Name Alternative
cancer/testis antigen 96 antibody CT96 antibody Dual specificity protein kinase TTK antibody ECSTY kinase antibody ESK antibody FLJ38280 antibody hMPS1 antibody Monopolar Spindle 1 Like 1 antibody MPH1 antibody Mps 1 antibody MPS1L1 antibody Phosphotyrosine Picked Threonine Kinase antibody Phosphotyrosine picked threonine-protein kinase antibody PYT antibody RP3-357D13.2 antibody ttk antibody TTK Protein Kinase antibody TTK_HUMAN antibody
Abbreviation
TTK
Swiss Prot
P33981 Human
Cellular Locus
Spindle, nucleus, cytoplasm, kinetochore, membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human TTK aa 1-300.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Human placenta tissue lysates, human lung tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, SH-SY5Y, MG-63.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000;IHC-P: 1:100;IF-Cell: 1:50;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 97 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No