NC2 alpha Rabbit Polyclonal Antibody

CAT: 0992-HA500224Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-HA500224Size:100 µL
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Description
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.
CAS Number
9007-83-4
Product Name Alternative
DR1 associated corepressor antibody DR1 associated protein 1 (negative cofactor 2 alpha) antibody DR1 associated protein 1 antibody DR1 associated protein1 antibody Dr1-associated corepressor antibody Dr1-associated protein 1 antibody DRAP 1 antibody Drap1 antibody NC 2 alpha antibody NC 2alpha antibody NC2 alpha antibody NC2-alpha antibody NC2A_HUMAN antibody Negative co-factor 2-alpha antibody Negative cofactor 2 alpha antibody Negative cofactor 2alpha antibody
Abbreviation
DRAP1
Swiss Prot
Q14919 Human, Q9D6N5 Mouse, A0JPP1 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human NC2 alpha aa 150-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
SW1990 cell lysate, Jurkat cell lysate, SK-Br-3 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, rat testis tissue, human cervix tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 22 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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