EZH1 Rabbit Polyclonal Antibody

EZH1 Rabbit Polyclonal Antibody

• Description: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation
• Product Name Alternative: Enhancer of zeste homolog 1 (Drosophila) antibody Enhancer of zeste homolog 1 antibody ENX-2 antibody ENX2 antibody Ezh1 antibody EZH1_HUMAN antibody Histone-lysine N-methyltransferase EZH1 antibody
• Abbreviation: Histone-lysine N-methyltransferase EZH1 KIAA0388 ENX-2 Enhancer of zeste homolog 1
• CAS Number: 9007-83-4
• Swiss Prot: Q92800 Human, P70351 Mouse, F1LZH3 Rat
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human EZH1 aa 500-747.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB
• Positive Control: Siha cell lysate, Hela cell lysate, mouse hippocampusl tissue lysate, rat brain tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 86/81/80/69 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No