ATBF1 Rabbit Polyclonal Antibody

• Description:

  This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.

• Product Name Alternative:

  Zinc finger homeobox protein 3 AT motif-binding factor 1 AT-binding transcription factor 1 Alpha-fetoprotein enhancer-binding protein Zinc finger homeodomain protein 3 ZFH-3 ZFHX3 ATBF1 C16orf47

• Abbreviation:

  ZFHX3

• Swiss Prot:

  Q15911 Human, F1M4Q6 Rat

• Cellular Locus:

  Nucleus, Cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat

• Immunogen:

  Recombinant protein within human ATBF1 aa 1,800-2,000.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IHC-P

• Positive Control:

  Rat esophagus tissue, human colon tissue, human breast carcinoma tissue, human stomach carcinoma tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:5,000 for recombinant protein; 1:500 for endogenous lysates (predicted) ;IHC-P: 1:100-1:500

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  404/306 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4