IL-7 Rabbit Polyclonal Antibody

• Description:

  Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor γ chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of insulin receptor substrate-1 (IRS-1) and insulin receptor substrate-2 (IRS-2), originally called 4PS.

• Product Name Alternative:

  IL 7 antibody IL-7 antibody Il7 antibody IL7_HUMAN antibody Interleukin 7 antibody Interleukin-7 antibody LP-1 antibody Lymphopoietin 1 antibody

• Abbreviation:

  Interleukin-7

• Swiss Prot:

  P13232 Human

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Synthetic peptide within human IL-7 aa 1-50.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  SHSY5Y cell lysate, HepG2 cell lysate, PANC-1, SH-SY5Y, SiHa, human tonsil tissue, human spleen tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500;IF-Cell: 1:50-1:100;IHC-P: 1:200-1:500

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  20/15 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4