IL-7 Rabbit Polyclonal Antibody

IL-7 Rabbit Polyclonal Antibody

• Description: Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor γ chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of insulin receptor substrate-1 (IRS-1) and insulin receptor substrate-2 (IRS-2), originally called 4PS.
• Product Name Alternative: IL 7 antibody IL-7 antibody Il7 antibody IL7_HUMAN antibody Interleukin 7 antibody Interleukin-7 antibody LP-1 antibody Lymphopoietin 1 antibody
• Abbreviation: Interleukin-7
• CAS Number: 9007-83-4
• Swiss Prot: P13232 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human IL-7 aa 1-50.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: SHSY5Y cell lysate, HepG2 cell lysate, PANC-1, SH-SY5Y, SiHa, human tonsil tissue, human spleen tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500;IF-Cell: 1:50-1:100;IHC-P: 1:200-1:500
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 20/15 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No