IL-8 Rabbit Polyclonal Antibody

IL-8 Rabbit Polyclonal Antibody

• Description: IL-8, also known as neutrophil chemotactic factor, has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also stimulates phagocytosis once they have arrived. IL-8 is also known to be a potent promoter of angiogenesis. In target cells, IL-8 induces a series of physiological responses required for migration and phagocytosis, such as increases in intracellular Ca2+, exocytosis (e.g. histamine release), and the respiratory burst.IL-8 can be secreted by any cells with toll-like receptors that are involved in the innate immune response. Usually, it is the macrophages that see an antigen first, and thus are the first cells to release IL-8 to recruit other cells. Both monomer and homodimer forms of IL-8 have been reported to be potent inducers of the chemokine receptors CXCR1 and CXCR2. The homodimer is more potent, but methylation of Leu25 can block the activity of homodimers.
• Product Name Alternative: (Ala-IL-8)77 antibody (Ser-IL-8)72 antibody 9E3 antibody Beta thromboglobulin like protein antibody C-X-C motif chemokine 8 antibody CEF-4 antibody chemokine, CXC motif, ligand 8 antibody CXCL8 antibody Emoctakin antibody GCP-1 antibody GCP/IL-8 protein I antibody GCP/IL-8 protein II antibody GCP/IL-8 protein III antibody GCP/IL-8 protein IV antibody GCP/IL-8 protein V antibody GCP/IL-8 protein VI antibody GCP1 antibody Granulocyte chemotactic protein 1 antibody IL-8 antibody IL-8 (1-77) antibody IL-8 (9-77) antibody IL8 antibody IL8/NAP1 form I antibody IL8/NAP1 form II antibody IL8/NAP1 form III antibody IL8/NAP1 form IV antibody IL8/NAP1 form V antibody IL8/NAP1 form VI antibody IL8_HUMAN antibody Inteleukin 8 antibody LECT antibody LUCT antibody Lymphocyte-derived neutrophil-activating factor antibody LYNAP antibody MDNCF antibody MDNCF-b antibody MDNCF-c antibody MONAP antibody Monocyte derived neutrophil activating peptide antibody Monocyte derived neutrophil chemotactic factor antibody Monocyte-derived neutrophil chemotactic factor antibody Monocyte-derived neutrophil-activating peptide antibody NAF antibody NAP 1 antibody NAP-1 antibody NAP1 antibody Neutrophil activating peptide 1 antibody Neutrophil activating protein 1 antibody Neutrophil-activating factor antibody Neutrophil-activating protein 1 antibody Protein 3 10C antibody Protein 3-10C antibody SCYB 8 antibody SCYB8 antibody Small inducible cytokine subfamily B member 8 antibody T cell chemotactic factor antibody T-cell chemotactic factor antibody TSG 1 antibody TSG1 antibody
• Abbreviation: Interleukin-8,IL-8,C-X-C motif chemokine 8,Chemokine (C-X-C motif) ligand 8,Emoctakin,Granulocyte chemotactic protein 1,GCP-1,Monocyte-derived neutrophil chemotactic factor,MDNCF,Monocyte-derived neutrophil-activating peptide,MONAP,Neutrophil-activating protein 1,NAP-1,Protein 3-10C,T-cell chemotactic factor,CXCL8
• CAS Number: 9007-83-4
• Swiss Prot: P10145 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within Human IL8 aa 1-99 / 99.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, IF-Cell, FC
• Positive Control: U-87 MG treated with 1μM Thapsigargin for 24 hours cell lysate, human tonsil tissue, human skeletal muscle tissue, AGS.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:50-1:100 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 11 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No