RACK1 Recombinant Rabbit Monoclonal Antibody [JG40-26]

RACK1 Recombinant Rabbit Monoclonal Antibody [JG40-26]

• Description: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellular receptors for activated PKC that may be involved in the activation-induced translocation of PKC. RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain. The RACK1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice and P.falciparum, and maps to human chromosome 5q35.3.
• Product Name Alternative: Cell proliferation-inducing gene 21 protein antibody GBLP_HUMAN antibody Gnb2-rs1 antibody Gnb2l1 antibody Guanine nucleotide binding protein (G protein) beta polypeptide 2 like 1 antibody Guanine nucleotide binding protein beta polypeptide 2 like 1 antibody Guanine nucleotide binding protein beta subunit 2 like 1 antibody Guanine nucleotide binding protein beta subunit like protein 12.3 antibody Guanine nucleotide binding protein subunit beta 2 like 1 antibody Guanine nucleotide binding protein subunit beta like protein 12.3 antibody Guanine nucleotide-binding protein subunit beta-2-like 1 antibody Guanine nucleotide-binding protein subunit beta-like protein 12.3 antibody H12.3 antibody HLC-7 antibody Human lung cancer oncogene 7 protein antibody lung cancer oncogene 7 antibody OTTHUMP00000223704 antibody OTTHUMP00000223870 antibody OTTHUMP00000223891 antibody OTTHUMP00000223893 antibody OTTHUMP00000223900 antibody OTTHUMP00000223902 antibody OTTHUMP00000223930 antibody OTTHUMP00000223931 antibody PIG21 antibody Proliferation inducing gene 21 antibody Protein homologous to chicken B complex protein guanine nucleotide binding antibody RACK1 antibody Receptor for activated C kinase 1 antibody Receptor for activated C kinase antibody Receptor of activated protein kinase C 1 antibody
• Abbreviation: HLC-7, RACK1, GNB2L1
• CAS Number: 9000-83-3
• Swiss Prot: P63244 Human, P63245 Rat
• Cellular Locus: Cytoplasm. Cell membrane. Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human RACK1 aa 190-317 / 317.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: SH-SY5Y cell lysate, Daudi cell lysate, rat cerebellum tissue, rat liver tissue, human colon tissue, mouse skin tissue, SH-SY5Y.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 35 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes