Tetranectin Recombinant Rabbit Monoclonal Antibody [JG37-16]

Tetranectin Recombinant Rabbit Monoclonal Antibody [JG37-16]

• Description: Tetranectin is a homotrimeric glycoprotein present in plasma and various tissue locations that binds to calcium, heparin, and plasminogen kringle 4. Tetranectin may play a prominent role in tissue remodeling as well as in the regulation of proteolytic processes via its binding and indirect activation of plasminogen. Tetranectin is found in the extracellular matrix (ECM) of certain carcinomas, but is not present in the ECM of normal tissues. Extracellular proteolysis is an important factor in the ability of malignant cells to penetrate normal tissues and metastasize. Decreased plasma tetranectin or increased tetranectin in stroma of cancers correlates with cancer progression and a grim prognosis. Tetranectin may also influence cancer growth by altering activities of plasminogen or the plasminogen fragment, angiostatin which inhibits tumor cell proliferation.
• Product Name Alternative: C type lectin domain family 3 member B antibody C-type lectin domain family 3 member B antibody Clec3b antibody Plasminogen kringle 4 binding protein antibody Plasminogen kringle 4-binding protein antibody TETN_HUMAN antibody Tetranectin (plasminogen binding protein) antibody Tetranectin antibody TN antibody TNA antibody
• Abbreviation: TN, CLEC3B, TNA
• CAS Number: 9000-83-3
• Swiss Prot: P05452 Human, P43025 Mouse
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human Tetranectin aa 110-202 / 202.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP
• Positive Control: Rat skin tissue lysate, human skin tissue lysate, HepG2, MCF-7, human liver carcinoma tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;IP: 1:10-1:50
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 23 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes