Reelin Recombinant Rabbit Monoclonal Antibody [JA63-13]

Reelin Recombinant Rabbit Monoclonal Antibody [JA63-13]

• Description: Reelin is a large secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates synaptic plasticity by enhancing the induction and maintenance of long-term potentiation. It also stimulates dendrite[9] and dendritic spine development and regulates the continuing migration of neuroblasts generated in adult neurogenesis sites like the subventricular and subgranular zones. It is found not only in the brain but also in the liver, thyroid gland, adrenal gland, Fallopian tube, breast and in comparatively lower levels across a range of anatomical regions.
• Product Name Alternative: LIS2 antibody PRO1598 antibody Reeler antibody Reelin antibody RELN antibody RELN_HUMAN antibody RL antibody
• Abbreviation: RELN
• CAS Number: 9000-83-3
• Swiss Prot: P78509 Human, Q60841 Mouse, P58751 Rat
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Reelin aa 3248-3297 / 3460.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IHC-Fr
• Positive Control: HepG2 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, rat brain tissue, mouse brain tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;IHC-Fr: 1:500
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 388 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes