Calcineurin A Recombinant Rabbit Monoclonal Antibody [JA64-11]

Calcineurin A Recombinant Rabbit Monoclonal Antibody [JA64-11]

• Description: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-Aα, PP2B-Aβ and PP2B-Aγ. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.
• Product Name Alternative: Alpha isoform formerly PPP2B antibody Calcineurin A alpha antibody Calcineurin A1 antibody CalcineurinA antibody Calmodulin dependent calcineurin A subunit alpha isoform antibody Calmodulin-dependent calcineurin A subunit alpha isoform antibody CALN antibody CALNA 1 antibody CALNA antibody CALNA1 antibody CAM PRP catalytic subunit antibody CAM-PRP catalytic subunit antibody CCN 1 antibody CCN1 antibody CNA 1 antibody CNA alpha antibody CNA antibody CNA1 antibody PP2BA_HUMAN antibody PPP2B antibody Ppp3ca antibody Protein phosphatase 2B catalytic subunit antibody Protein phosphatase 3 (formerly 2B) catalytic subunit alpha isoform antibody Protein phosphatase 3 catalytic subunit alpha isoform PPP3CA antibody Protein phosphatase 3 catalytic subunit alpha isozyme antibody Serine/threonine protein phosphatase 2B catalytic subunit alpha isoform antibody Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform antibody
• Abbreviation: PPP3CA
• CAS Number: 9000-83-3
• Swiss Prot: Q08209 Human, P63328 Mouse, P63329 Rat
• Cellular Locus: Cell membrane, Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Calcineurin A aa 472-521 / 521.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, FC
• Positive Control: Hela cell lysate, 293 cell lysate, A431 cell lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brain tissue lysate, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 59 kD
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes