VAMP8 Recombinant Rabbit Monoclonal Antibody [JF0963]

VAMP8 Recombinant Rabbit Monoclonal Antibody [JF0963]

• Description: Vesicle-associated membrane protein 8 is a protein that in humans is encoded by the VAMP8 gene.Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment. It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex.Phosphorylation of VAMP8 inside the conserved SNARE-domain can suppress vesicle fusion.
• Product Name Alternative: EDB antibody Endobrevin antibody VAMP 8 antibody VAMP-8 antibody VAMP8 antibody VAMP8_HUMAN antibody Vesicle associated membrane protein 8 antibody Vesicle-associated membrane protein 8 antibody
• Abbreviation: VAMP-8, EDB, VAMP8
• CAS Number: 9000-83-3
• Swiss Prot: Q9BV40 Human, O70404 Mouse, Q9WUF4 Rat
• Cellular Locus: Lysosome membrane, Early endosome membrane, Late endosome membrane, Cell membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide wiithin Human VAMP8 aa1-29 / 100.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
• Positive Control: Hela cell lysate, mouse kidney tissue lysate, U937 cell lysates, SW480, 293T, Hela, human kidney tissue, mouse kidney tissue, rat kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:1,000 ;IHC-P: 1:5,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 11 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes