PDPK1 Recombinant Rabbit Monoclonal Antibody [SD204-9]

PDPK1 Recombinant Rabbit Monoclonal Antibody [SD204-9]

• Description: PDPK1 (3-phosphoinositide dependent protein kinase 1), also known as PDK1, PDPK2, PDPK2P or PRO0461, is 556 amino acid ubiquitously expressed protein that localizes to the cell membrane, cytoplasm and nucleus. Acting as a master kinase, PDPK1 phosphorylates and activates a subgroup of the AGC family of protein kinases. PDPK1 is involved in mediating signal transduction for controlling proliferation, survival, and growth of developing pancreatic beta cells, regulating Ca2+ uptake and Ca2+-activated K+ channels of mast cells, regulation of chemotaxis and motility of vascular endothelial cells, cardiac homeostasis, and thymocyte development. Belonging to the protein kinase superfamily, PDPK1 contains a PH domain, which play an essential role in homodimerization, localization and nuclear import of PDPK1, and a protein kinase domain. PDPK1 exists as five alternatively spliced isoforms and is encoded by a gene located on human chromosome 16p13.3.
• Product Name Alternative: 3 phosphoinositide dependent protein kinase 1 antibody 3-phosphoinositide-dependent protein kinase 1 antibody hPDK 1 antibody hPDK1 antibody MGC20087 antibody MGC35290 antibody OTTHUMP00000159109 antibody OTTHUMP00000159110 antibody OTTHUMP00000174525 antibody PDK1 antibody Pdpk1 antibody PDPK1_HUMAN antibody PDPK2 antibody PDPK2P antibody PkB kinase antibody PkB kinase like gene 1 antibody PkB like 1 antibody PRO0461 antibody Protein kinase antibody
• Abbreviation: hPDK1
• CAS Number: 9000-83-3
• Swiss Prot: O15530 Human, Q9Z2A0 Mouse, O55173 Rat
• Cellular Locus: Cell membrane, Nucleus, Cytoplasm, focal adhesion.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human PDPK1 aa 1-50 / 556.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P
• Positive Control: 293T cell lysate, PC-12 cell lysate, HL-60 cell lysate, Hela, MCF-7, SW480, human breast carcinoma tissue, mouse kidney tissue, human colon carcinoma tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 63 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes