PPP1R1A Recombinant Rabbit Monoclonal Antibody [SN0756]

PPP1R1A Recombinant Rabbit Monoclonal Antibody [SN0756]

• Description: The inhibitor of protein phosphatase 1 (IPP-1, I-1) plays a role in regulating the phosphorylation of other proteins, and is itself phosphorylated by a cyclic AMP-dependent protein kinase. IPP-1 is present in skeletal muscles and in distinct neuronal systems of the brain. The localization and expression of IPP-1 suggests that it may play discrete roles in certain regions and developing stages of the brain, independent of the regulation of protein phosphatase type 1 (PP-1). PP-1 binds to both phosphorylated and dephosphorylated IPP-1. Conversion of PP-1 to an Mn2+-dependent state appears to play a role in its regulation by IPP-1. IPP-1 attenuates the activity of glycogen phosphorylase and is thought to play an important role in the hormonal control of glycogen metabolism.
• Product Name Alternative: I 1 antibody I-1 antibody I1 antibody Inhibitor 1 antibody IPP 1 antibody IPP-1 antibody IPP1 antibody Ppp1r1a antibody PPR1A_HUMAN antibody Protein phosphatase 1 regulatory (inhibitor) subunit 1A antibody Protein phosphatase 1 regulatory subunit 1A antibody Protein phosphatase inhibitor 1 antibody
• Abbreviation: I-1, IPP-1, PPP1R1A
• CAS Number: 9000-83-3
• Swiss Prot: Q13522 Human, Q9ERT9 Mouse, P19103 Rat
• Cellular Locus: Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human PPP1R1A aa 1-50 / 171.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
• Positive Control: Mouse brain tissue lysate, rat brain tissue lysate, N2A, SH-SY5Y, SHG-44, human kidney tissue, human pancreas tissue, mouse kidney tissue, mouse pancreas tissue, rat kidney tissue, rat pancreas tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:1,000 ;IHC-P: 1:5,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 19 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes