BCL2A1 Recombinant Rabbit Monoclonal Antibody [SC05-42]

BCL2A1 Recombinant Rabbit Monoclonal Antibody [SC05-42]

• Description: The Bcl-2 family of proteins is characterized by its ability to modulate cell death under a broad range of physiological conditions. Bcl-2 and Bcl-xL function to inhibit apoptosis while other members of the Bcl-2 family, Bax, Bad, Bak and Bcl-xS, oppose death-suppressing effects. An additional member of the family, A1 (also designated Bfl-1), dimerizes with both Bcl-2 and Bax and has been identified as a hematopoietic- specific, early inducible gene. While A1 demonstrates life promoting properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. There is evidence that a correlation exists between a high expression of the A1 gene product and stomach cancer.
• Product Name Alternative: ACC 1 antibody ACC 2 antibody B2LA1_HUMAN antibody Bcl 2 related protein A1 antibody Bcl-2-like protein 5 antibody Bcl-2-related protein A1 antibody BCL2 related protein A1 antibody Bcl2-L-5 antibody BCL2A1 antibody BCL2L5 antibody BFL1 antibody GRS antibody HBPA1 antibody Hematopoietic BCL2 related protein A1 antibody Hemopoietic specific early response protein antibody Hemopoietic-specific early response protein antibody Protein BFL 1 antibody Protein BFL-1 antibody Protein GRS antibody
• Abbreviation: Bcl2-L-5, BCL2A1
• CAS Number: 9000-83-3
• Swiss Prot: Q16548 Human, Q07440 Mouse
• Cellular Locus: Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human BCL2A1 aa 2-48 / 175.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: Human tonsil tissue, human kidney tissue, mouse liver tissue, mouse kidney tissue, 293, human liver tissue, human kidney tissue lysates.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P:1:50-1:400 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 20 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes