alpha+beta Synuclein Recombinant Rabbit Monoclonal Antibody [ST05-21]

alpha+beta Synuclein Recombinant Rabbit Monoclonal Antibody [ST05-21]

• Description: The synucleins, including α-synuclein (also designated NACP for nonamyloid component precursor), β-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and γ-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-Synuclein, identified as a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of α-synuclein and β-synuclein may be important during hematopoetic cell differentiation. A mutant form of α-synuclein is found in patients with early onset Parkinson’s disease. γ-Synuclein is associated with axonal pathology in Parkinson’s disease.
• Product Name Alternative: Alpha synuclein antibody Beta synuclein antibody NACP antibody Non A beta component of AD amyloid antibody PARK1 antibody PARK4 antibody PD1 antibody SNCA antibody SNCB antibody Synuclein alpha antibody Synuclein beta antibody
• Abbreviation: NACP, SNCA, NACP, PARK1, SNCB
• CAS Number: 9000-83-3
• Swiss Prot: P37840 Human, Q16143 Human, O55042 Mouse, Q91ZZ3 Mouse, P37377 Rat, Q63754 Rat
• Cellular Locus: Cytoplasm, Nucleus, Membrane, Secreted, Cell junction.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human alpha+beta Synuclein aa 2-50 / 140.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: Mouse brain tissue lysate, rat brain tissue lysate, Hela, N2A, SH-SY5Y, human brain tissue, mouse brain tissue, rat brain tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:5,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 14 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes