c-Kit Recombinant Rabbit Monoclonal Antibody [ST04-99]

c-Kit Recombinant Rabbit Monoclonal Antibody [ST04-99]

• Description: The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
• Product Name Alternative: C Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody Mast/stem cell growth factor receptor Kit antibody MGF antibody p145 c-kit antibody PBT antibody Piebald trait protein antibody Proto oncogene c Kit antibody Proto oncogene tyrosine protein kinase Kit antibody Proto-oncogene c-Kit antibody SCF Receptor antibody SCFR antibody soluble KIT variant 1 antibody Steel Factor Receptor antibody Stem cell factor receptor antibody tyrosine protein kinase Kit antibody Tyrosine-protein kinase Kit antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody
• Abbreviation: SCFR, PBT, KIT
• CAS Number: 9000-83-3
• Swiss Prot: P10721 Human, P05532 Mouse
• Cellular Locus: Cell membrane, Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within C-terminal human KIT.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: Human brain tissue lysates, Saos-2 cell lysate, human breast tissue, human gastrointestinal stromal tumor tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 110 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes