c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938]

c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938]

• Description: Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.[5] It is encoded in humans by the FOS gene. It was first discovered in rat fibroblasts as the transforming gene of the FBJ MSV (Finkel–Biskis–Jinkins murine osteogenic sarcoma virus) (Curran and Tech, 1982). It is a part of a bigger Fos family of transcription factors which includes c-Fos, FosB, Fra-1 and Fra-2.It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein, which forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes and converts extracellular signals into changes of gene expression.It plays an important role in many cellular functions and has been found to be overexpressed in a variety of cancers.
• Product Name Alternative: Activator protein 1 antibody AP 1 antibody C FOS antibody Cellular oncogene c fos antibody Cellular oncogene fos antibody FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody FBJ murine osteosarcoma viral oncogene homolog antibody FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus antibody FOS antibody FOS protein antibody FOS_HUMAN antibody G0 G1 switch regulatory protein 7 antibody G0/G1 switch regulatory protein 7 antibody G0S7 antibody Oncogene FOS antibody p55 antibody proto oncogene c Fos antibody Proto oncogene protein c fos antibody Proto-oncogene c-Fos antibody v fos FBJ murine osteosarcoma viral oncogene homolog antibody
• Abbreviation: FOS
• CAS Number: 9000-83-3
• Swiss Prot: P01100 Human, P01101 Mouse, P12841 Rat
• Cellular Locus: Nucleus, Endoplasmic reticulum, Cytoplasm.
• Host: Rabbit
• Species Reactivity: Mouse, Human, Rat
• Immunogen: Synthetic peptide within Human c-Fos aa 231-268 / 380.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, FC, IF-Cell
• Positive Control: Human placenta tissue, NIH/3T3, NIH/3T3 cell lysate, MCF-7 cell lysate, HeLa serum starved for 40 hours then treated with 20% FBS for 2 hours.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IF-Cell:1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 41 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes