c-Myc Recombinant Rabbit Monoclonal Antibody [JE01-20]

c-Myc Recombinant Rabbit Monoclonal Antibody [JE01-20]

• Description: Myc proteins are transcription factors that activate expression of many pro-proliferative genes through binding enhancer box sequences (E-boxes) and recruiting histone acetyltransferases (HATs). Myc is thought to function by upregulating transcript elongation of actively transcribed genes through the recruitment of transcriptional elongation factors. It can also act as a transcriptional repressor. By binding Miz-1 transcription factor and displacing the p300 co-activator, it inhibits expression of Miz-1 target genes. In addition, myc has a direct role in the control of DNA replication.This activity could contribute to DNA amplification in cancer cells.
• Product Name Alternative: AU016757 antibody Avian myelocytomatosis viral oncogene homolog antibody bHLHe39 antibody c Myc antibody Cellular myelocytomatosis oncogene antibody Class E basic helix-loop-helix protein 39 antibody MGC105490 antibody MRTL antibody Myc antibody Myc protein antibody Myc proto oncogene protein antibody Myc proto-oncogene protein antibody myc-related translation/localization regulatory factor antibody MYC_HUMAN antibody Myc2 antibody myca antibody MYCC antibody Myelocytomatosis oncogene a antibody Myelocytomatosis oncogene antibody Niard antibody Nird antibody oncogene c-Myc antibody Oncogene Myc antibody OTTHUMP00000158589 antibody OTTHUMP00000227763 antibody Proto-oncogene c-Myc antibody Protooncogene homologous to myelocytomatosis virus antibody RNCMYC antibody Transcription factor p64 antibody Transcriptional regulator Myc-A antibody V-Myc avian myelocytomatosis viral oncogene homolog antibody v-myc myelocytomatosis viral oncogene homolog (avian) antibody zc-myc antibody
• Abbreviation: Myc proto-oncogene protein Class E basic helix-loop-helix protein 39 (bHLHe39) Proto-oncogene c-Myc Transcription factor p64
• CAS Number: 9000-83-3
• Swiss Prot: P01106 Human, P01108 Mouse, P09416 Rat
• Cellular Locus: Nucleus, nucleoplasm, nucleolus, Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Monkey
• Immunogen: Synthetic peptide.
• Isotype: IgG
• Clone: JE01-20
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell
• Positive Control: HeLa cell lysate, A549 cell lysate, HepG2 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, C6 cell lysate, COS-1 cell lysate, HeLa, NIH/3T3.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 50 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes