PKC beta 2 Recombinant Rabbit Monoclonal Antibody [ST48-06]

PKC beta 2 Recombinant Rabbit Monoclonal Antibody [ST48-06]

• Description: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional PKC isoforms (α, βI, βII and γ) and novel PKC isoforms. Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and é are independent of Ca2+. On the other hand, nPKC δ and ε, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
• Product Name Alternative: KPCB_HUMAN antibody PKC Beta antibody PKC-B antibody PKC-beta antibody PKCB antibody Prkcb antibody PRKCB II antibody PRKCB2 antibody Protein kinase C beta antibody Protein kinase C beta type antibody
• Abbreviation: PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1
• CAS Number: 9000-83-3
• Swiss Prot: P05771 Human, P68404 Mouse, P68403 Rat
• Cellular Locus: Nucleus, Cytoplasm, Membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human PKC beta 2 aa 615-660 / 671.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
• Positive Control: Raji cell lysates, SH-SY5Y, human spleen tissue, mouse brain tissue, mouse spleen tissue, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 77 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes