Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28]
CAT:
992-ET1608-22
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
![Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28] - image 1](/gentaur-product-1.webp)
Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28]
- Description: Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. The complex translocates into the nucleus for the transcriptional activation of interferons alpha and beta, and further interferon-induced genes.
- Product Name Alternative: IIAE7 antibody Interferon regulatory factor 3 antibody IRF 3 antibody IRF-3 antibody IRF3 antibody IRF3_HUMAN antibody MGC94729 antibody
- Abbreviation: IRF-3, IRF3
- CAS Number: 9000-83-3
- Swiss Prot: Q14653 Human, P70671 Mouse
- Cellular Locus: Cytoplasm, Nucleus, Mitochondrion.
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser386 of human IRF3.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Recombinant Rabbit monoclonal Antibody
- Applications: WB, IF-Cell, IF-Tissue
- Positive Control: MCF7 treated with 100nM Calyculin A for 30 minutes whole cell lysate, NIH/3T3 treated with 100nM Calyculin A for 30 minutes cell lysate, MCF-7.
- Concentration: 1 mg/mL
- Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200
- Purity: Protein A affinity purified.
- Form: Liquid
- Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 47 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Recombinant Antibody: Yes