TCF3 Recombinant Rabbit Monoclonal Antibody [SY0258]

TCF3 Recombinant Rabbit Monoclonal Antibody [SY0258]

• Description: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and heterooligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.
• Product Name Alternative: AGM8 antibody bHLHb21 antibody Class B basic helix-loop-helix protein 21 antibody E12 antibody E2A antibody E2A immunoglobulin enhancer binding factors E12/E47 antibody E47 antibody Helix loop helix protein HE47 antibody Immunoglobulin enhancer-binding factor E12/E47 antibody Immunoglobulin transcription factor 1 antibody ITF1 antibody Kappa-E2-binding factor antibody MGC129647 antibody MGC129648 antibody Negative vitamin D response element binding protein antibody NOL1-TCF3 fusion antibody TCF-3 antibody Tcf3 antibody TFE2_HUMAN antibody transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody Transcription factor 3 antibody transcription factor 3 variant 3 antibody Transcription factor E2-alpha antibody Transcription factor ITF-1 antibody VDIR antibody VDR interacting repressor antibody vitamin D receptor-interacting repressor antibody
• Abbreviation: bHLHb21, TCF-3, TCF3
• CAS Number: 9000-83-3
• Swiss Prot: Q9HCS4 Human
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human TCF3 aa 71-120 / 588.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, FC
• Positive Control: 293
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 67 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes