Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01]

Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01]

• Description: Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated Myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin), are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.
• Product Name Alternative: Basic calponin antibody Calponin 1 antibody Calponin 1 basic smooth muscle antibody Calponin H1 antibody Calponin H1 smooth muscle antibody Calponin-1 antibody Calponin1 antibody Calponins basic antibody CNN 1 antibody Cnn1 antibody CNN1_HUMAN antibody Epididymis secretory protein Li 14 antibody HEL S 14 antibody Sm Calp antibody SMCC antibody smooth muscle antibody
• Abbreviation: CNN1
• CAS Number: 9000-83-3
• Swiss Prot: P51911 Human, Q08091 Mouse, Q08290 Rat
• Cellular Locus: Cytoskeleton,focal adhesion.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Calponin aa 248-297 / 297.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P
• Positive Control: Mouse stomach tissue lysate, Rat stomach tissue lysate, Hela cell lysate, NIH/3T3 cell lysate, HepG2, mouse colon tissue, rat colon tissue, rat stomach tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:5,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 33 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes