Integrin alpha 6 Recombinant Rabbit Monoclonal Antibody [SR45-00]

Integrin alpha 6 Recombinant Rabbit Monoclonal Antibody [SR45-00]

• Description: Integrin alpha-6 is a protein that in humans is encoded by the ITGA6 gene. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. Specific loss of this integrin chain in the intestinal epithelium, and thus of their hemidesmosomes, induces long-standing colitis and infiltrating adenocarcinomas.
• Product Name Alternative: Alpha6p antibody CD49 antigen-like family member F antibody CD49f antibody Integrin alpha6B antibody Integrin, alpha 6 antibody ITA6_HUMAN antibody ITGA6 antibody ITGA6B antibody Processed integrin alpha-6 antibody VLA 6 antibody VLA-6 antibody
• Abbreviation: ITGA6
• CAS Number: 9000-83-3
• Swiss Prot: P23229 Human, Q61739 Mouse, Q63258 Rat
• Cellular Locus: Cell membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human Integrin alpha 6 aa 1-100.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: A431 cell lysate, SW480 cell lysate, human colon carcinoma tissue, mouse colon tissue, mouse stomach tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:50-1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 127 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes