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Integrin alpha 3 Rabbit Polyclonal Antibody

CAT: 0992-HA500111Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500111Size:100 µL
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Description
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin. ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'), very common antigen 2 ('VCA-2'), extracellular matrix receptor 1 ('ECMR1'), and galactoprotein b3 ('GAPB3'). Expression of this gene may be correlated with breast cancer metastasis.
CAS Number
9007-83-4
Product Name Alternative
AA407068 antibody Antigen identified by monoclonal antibody J143 antibody CD49 antigen like family member C antibody CD49 antigen-like family member C antibody CD49c antibody CD49c antigen antibody FLJ34631 antibody FLJ34704 antibody FRP 2 antibody FRP-2 antibody FRP2 antibody Galactoprotein B3 antibody GAP B3 antibody GAPB3 antibody Integrin alpha 3 antibody Integrin alpha-3 light chain antibody Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody ITA3_HUMAN antibody ITGA 3 antibody Itga3 antibody MSK18 antibody VCA 2 antibody VCA2 antibody Very late activation protein 3 receptor alpha 3 subunit antibody VL3A antibody VLA 3 alpha chain antibody VLA 3 subunit alpha antibody VLA-3 subunit alpha antibody VLA3a antibody
Abbreviation
ITGA3
Swiss Prot
P26006 Human, D3ZCG9 Rat
Cellular Locus
Cell membrane, invadopodium membrane, filopodium membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human Integrin alpha 3 aa 33-220.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
A549 cell lysate, human stomach tissue lysate, rat kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:10-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 117 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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