Clusterin Rabbit Polyclonal Antibody

Clusterin Rabbit Polyclonal Antibody

• Description: Detected in blood plasma, cerebrospinal fluid, milk, seminal plasma and colon mucosa. Detected in the germinal center of colon lymphoid nodules and in colon parasympathetic ganglia of the Auerbach plexus (at protein level). Ubiquitous. Detected in brain, testis, ovary, liver and pancreas, and at lower levels in kidney, heart, spleen and lung.Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis.In humans, clusterin is encoded by the CLU gene on chromosome CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging.
• Product Name Alternative: 40 antibody AAG 4 antibody AAG4 antibody Aging associated protein 4 antibody Aging-associated gene 4 protein antibody AI893575 antibody APO J antibody Apo-J antibody APOJ antibody ApoJalpha antibody ApoJbeta antibody Apolipoprotein J antibody ApolipoproteinJ antibody CLI antibody CLU antibody CLU1 antibody CLU2 antibody CLUS_HUMAN antibody Clusterin alpha chain antibody Clusterin antibody Clusterin beta chain antibody Complement associated protein SP 40 40 antibody Complement associated protein SP 40 antibody Complement associated protein SP40 antibody Complement cytolysis inhibitor a chain antibody Complement cytolysis inhibitor antibody Complement cytolysis inhibitor b chain antibody Complement lysis inhibitor antibody Complement-associated protein SP-40 antibody D14Ucla3 antibody Dimeric acid glycoprotein antibody Glycoprotein 80 antibody Glycoprotein III antibody GP80 antibody Ku70-binding protein 1 antibody KUB 1 antibody KUB1 antibody MGC24903 antibody NA1/NA2 antibody RATTRPM2B antibody SGP 2 antibody SGP2 antibody SP 40 antibody SP40 antibody Sugp-2 antibody Sulfated glycoprotein 2 antibody Testosterone repressed prostate message 2 antibody Testosterone-repressed prostate message 2 antibody TRPM 2 antibody TRPM-2 antibody TRPM2 antibody TRPM2B antibody Trpmb antibody
• Abbreviation: Clusterin,Aging-associated gene 4 protein,Apolipoprotein J,Apo-J,Complement cytolysis inhibitor,CLI,Complement-associated protein SP-40,40,Ku70-binding protein 1 NA1/NA2,Sulfated glycoprotein 2,Testosterone-repressed prostate message 2,TRPM-2,Clusterin beta chain ApoJalpha Complement cytolysis inhibitor a chain Clusterin alpha chain ApoJbeta Complement cytolysis inhibitor b chain SGP-2 CLU
• CAS Number: 9007-83-4
• Swiss Prot: P10909 Human
• Cellular Locus: Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Microsome, Mitochondrion, Nucleus, Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human Clusterin aa350-449.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: Hela cell lysate, SKBR-3 cell lysate, human tonsil tissue, human pancreas tissue, A549.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:100-1:500 ;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 52 kDa.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No