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CD35 Rabbit Polyclonal Antibody

CAT: 0992-ER2001-14Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-ER2001-14Size:100 µL
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Description
Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages . Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation . Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells .
CAS Number
9007-83-4
Product Name Alternative
C3 binding protein antibody C3b/C4b receptor antibody C3BR antibody C4BR antibody CD 35 antibody CD35 antibody CD35 antigen antibody complement component (3b/4b) receptor 1 (Knops blood group) antibody complement component (3b/4b) receptor 1 including Knops blood group system antibody Complement component receptor 1 antibody Complement receptor 1 antibody Complement receptor type 1 antibody CR 1 antibody CR1 antibody CR1_HUMAN antibody KN antibody Knops blood group antigen antibody
Abbreviation
Complement receptor type 1 CR1 C3b/C4b receptor CD35
Swiss Prot
P17927 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human Complement receptor type 1 aa 600-800.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HL-60 cell lysates, recombinant protein lysates, human spleen tissue, human kidney tissue, Daudi.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1;50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 224 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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