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CD34 Rabbit Polyclonal Antibody

CAT: 0992-ER1706-66Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1706-66Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. However, little is known about its exact function. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia, whereas the L-selectin to which it binds is on the T cell. Conversely, under other circumstances CD34 has been shown to act as molecular "Teflon" and block mast cell, eosinophil and dendritic cell precursor adhesion, and to facilitate opening of vascular lumina. CD34 may also play a more selective role in chemokine-dependent migration of eosinophils and dendritic cell precursors. Regardless of its mode of action, under all circumstances CD34, and its relatives podocalyxin and endoglycan, facilitates cell migration.
CAS Number
9007-83-4
Product Name Alternative
CD34 antibody CD34 antigen antibody CD34 molecule antibody CD34_HUMAN antibody Cluster designation 34 antibody Hematopoietic progenitor cell antigen CD34 antibody HPCA1 antibody Mucosialin antibody OTTHUMP00000034733 antibody OTTHUMP00000034734 antibody
Abbreviation
CD34
Swiss Prot
P28906 Human, Q64314 Mouse
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human CD34 aa 10-310/385.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
TF-1, human brain tissue lysate, human liver cancer tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-2,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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