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CD34 Rabbit Polyclonal Antibody

CAT: 0992-ER0802Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER0802Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC.
CAS Number
9007-83-4
Product Name Alternative
CD34 antibody CD34 antigen antibody CD34 molecule antibody CD34_HUMAN antibody Cluster designation 34 antibody Hematopoietic progenitor cell antigen CD34 antibody HPCA1 antibody Mucosialin antibody OTTHUMP00000034733 antibody OTTHUMP00000034734 antibody
Abbreviation
CD34
Swiss Prot
P28906 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Synthetic peptide within Human CD34 aa 336-385 / 385.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
TF-1 cell lysate, human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, TF-1, human tonsil tissue, human liver carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:250 ;IHC-P: 1:2,000-1:3,000 ;FC: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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